VIROLOGY:
Study of virus is termed as virology.
A virus is a biological agent that replicates inside the cells of living organisms.
it can affect all life forms, be it animals,plants or micro-organisms like bacteria,etc.
When a host cell is infected by a virus there is forced production of thousands of identical copies of the original virus at an extraordinary rate. Viruses do not have cells that divide; new viruses are assembled in the infected host cell and its DNA gets damaged. The host cell is unable to repair itself and can't perform its functions properly.
Most virus infections eventually result in the death of the host cell.
The CoronaVirus gets transmitted via aerosoldroplets (after someone affected with coronavirus disease sneezes or coughs nearby) or by direct contact (when you touch a contaminated surface (fomites) and then touch your face, nose or mouth.
initially the virus infects the cells of throat, airways and lungs and starts replicating therby turning them into "coronavirus industries/factories" that produce huge numbers of new viruses which in turn infects more cells.
At this early stage, there is no sign and symptom of sickness and some people may never develop symptoms (asymtomatic cases).
The incubation period (the time between catching the viral infection and beginning to have symptoms of disease).
Most estimates of the incubation period of 1-14 days, most commonly it is 5 days on average.
Symptoms:
The arrival of the symptoms:
Once you get affected by the coronavirus, after a period of 5-6 days there will be some mild symptoms similar to symptoms of flu.
•Mild symptoms :
There may be body aches, sore throat, runny nose, headache with fever and dry cough.
Fever is a result of your immune system which responds to the entry and replication of the coronavirus. It markes the virus as a hostile invader and signals out that something is wrong in the body by releasing chemicals called cytokines and activates the thermostat to increase the body temperature (as an attempt to kill the invading organism).
Dry Cough is caused due irritation of cells by infection and multiplication of invading virus.
Some people might have productive cough which means they cough up sputum (a thick mucus containing dead lung cells killed by the virus).
There may be fatigue, nausea, vomiting, abdominal pain, diarrhoea, muscle or joint pain.
•Severe symptoms
If no medical treatment is done for the mild symptoms and thus the immunity system gets weakend, the virus replicates at a extraordinary rate and affects the alveolar sacs inside the lungs (majority cases).
There is dyspnoea (difficulty in breathing), high fever, chest pain, hemoptysis (blood vomiting), respiratory crackles and insuffiency.
Inflammation of the lungs is called Pneumonia which can eventually cause shortness of breath and difficulty in breathing. Mostly it is bilateral pnuemonia (affecting both lungs).
With pneumonia, the air sacs may fill with fluid or pus and it becomes difficult for air to pass.
People may need nebulizer or ventilator to breathe in properly.
• Critical symptoms
If pneumonia gets unchecked or uncontrolled then it may damage the lungs to a large extent. The immune system becomes very weak and is unable to cope up.
Complications can lead to cardiac inury, myocarditis, arrhythmia, liver dysfunction and septic shock (when the blood pressure drops to dangerously low levels).
Acute respiratory distress syndrome (ARDS) caused by widespread inflammation in the lungs may result in systemic inflammatory response syndrome (SIRS) or sepsis. This further evolves to acute renal failure (kidney damage) and multiple-organ failure (organs stop working properly or fail completely).
Finally the damage can reach fatal levels at which organs can no longer keep the body alive and eventually leads to death.